Targeted Chemotherapy for Liver Cancer
Transarterial Chemoembolization (TACE)
About Transarterial Chemoembolization (TACE)
Transarterial Chemoembolization, commonly known as TACE, is an advanced interventional radiology technique aimed at treating primary and metastatic liver cancers. Unlike traditional chemotherapy that circulates throughout the entire body, TACE delivers high doses of chemotherapy drugs directly to the tumor. This procedure combines the infusion of chemotherapeutic agents with embolization, which is the process of blocking the blood vessels feeding the tumor. By doing so, TACE achieves a twofold effect: it cuts off the tumor’s blood supply and traps the chemotherapy drugs at the site of the tumor, allowing for higher local concentrations of the drugs with minimal systemic exposure.
TACE is particularly beneficial for patients with liver tumors that are not suitable for surgical removal. It is often used for hepatocellular carcinoma (HCC), the most common type of primary liver cancer, as well as for cancers that have spread to the liver from other parts of the body, such as colorectal cancer, breast cancer, and neuroendocrine tumors. The precision and targeted nature of TACE make it a preferred option for managing liver tumors, providing a therapeutic approach that focuses on maximizing treatment efficacy while minimizing adverse effects.
Conditions TACE Treats
TACE is primarily used to treat various types of liver tumors. The conditions it treats include:
- Hepatocellular Carcinoma (HCC): This is the most common type of primary liver cancer. TACE is particularly effective for patients whose tumors are not suitable for surgical removal.
- Metastatic Liver Cancer: These are cancers that have spread to the liver from other parts of the body. TACE can be used to manage and treat metastases from:
- Colorectal cancer
- Breast cancer
- Neuroendocrine tumors
- Ocular melanoma
- Sarcoma
Benefits and Effectiveness of TACE
Transarterial Chemoembolization (TACE) offers several significant benefits:
- Targeted Treatment: High-dose chemotherapy is delivered directly to the tumor, minimizing exposure to the rest of the body.
- Preserved Liver Function: Blocking the hepatic artery does not significantly impact liver function, as blood flow continues from the portal vein.
- High Success Rate: TACE can halt tumor growth in about 70% of patients.
- Minimally Invasive: TACE typically involves shorter recovery times and less discomfort compared to surgery.
Risks
While TACE is generally considered safe, it is important to be aware of potential risks associated with the procedure:
- Infection: A small risk of infection exists at the incision site.
- Bleeding: Insertion of the catheter can cause bleeding, especially in patients with blood clotting issues.
- Liver Damage: There is a risk of damaging healthy liver tissue if chemotherapy drugs or embolic agents affect areas outside the tumor.
- Post-Embolization Syndrome: Flu-like symptoms may occur after the procedure, typically managed with pain relievers and rest.
- Kidney Damage: Risk of kidney damage, particularly in patients with pre-existing conditions, managed through careful monitoring.
- Blood Clots: There is a risk of blood clots, especially in pediatric patients.
Contact Florida Radiology Consultants About TACE
For more information about Transarterial Chemoembolization (TACE) and other advanced interventional radiology treatments, contact Florida Radiology Consultants today. As experts in interventional radiology, we provide cutting-edge treatments like TACE to patients in Southwest Florida, including Cape Coral, Fort Myers, and the surrounding areas. Our team is dedicated to offering precise, effective care for liver cancer and metastatic liver disease.
= Hospital Location 
= Outpatient Location